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Acute respiratory distress syndrome (ARDS) is a life-threatening illness that usually requires ICU care.  ARDS survivors frequently experience new or worsening physical, cognitive, and/or mental health impairments that last for years.  However some ARDS survivors adapt to new impairments over time and report improving quality of life not explained by improvements in their physical, cognitive, and mental health.  This adaption phenomenon is known as “response shift.”  We are exploring whether patient characteristics prior to ARDS are associated with the magnitude of response shift experienced after ICU discharge, as well as how psycho-social factors like social support, resilience, and survivors’ expectations for recovery impact quality of life.  This research uses data from the NHLBI ARDS Network Long Term Outcome Study (ALTOS) containing hundreds of data elements per patient, as well as enrolling a new prospective cohort of ICU survivors to collect data on the association between patient expectations for recovery and perceived quality of life 6 months after hospital discharge. 

Funding: NIH NHLBI K01HL141637    

A collaboration with: Outcomes After Critical Illness & Surgery